Discussion Map

Where to ask, debate, and contribute — substantive discussion is unified; process is split by activity

Quick links: All GitHub Discussions · Substantive hub (#3) · PQ framing hub (#4) · Workshop hub (#2) · Platform & UX hub (#16)

The structure

Substantive discussion is unified. Biology, economics, statistics, engineering, and welfare debates happen in one place — the Substantive discussion hub — rather than fragmenting across Workshop / Model / PQ silos.

Process discussion is split by activity — three separate hubs for three distinct coordination tasks: workshop logistics, PQ framing, and platform/UX.

GitHub Discussions is a flat stack of threads per category; the structure below is maintained by hand.

Quick decision tree

I want to…	Use…
Comment on a specific line, paragraph, parameter, or equation	Hypothesis — click the `<` tab on the right edge of any dashboard page (a free Hypothesis account is required, signup takes ~30 seconds)
Debate actual cost values, biology, engineering, welfare, or methodology	Substantive hub (#3)
Discuss how to frame a Pivotal Question (resolution, jurisdiction fork, retiring/splitting)	PQ framing hub (#4)
Discuss workshop logistics, scheduling, session format	Workshop hub (#2)
Suggest UX, visual, page-layout, or commenting-tool improvements	Platform & UX hub (#16)
Report a code bug	GitHub Issues

Reading GitHub Discussions is open to everyone; posting requires a free GitHub account.

Substantive discussion (unified)

Hub: #3 Substantive discussion hub · category: Q&A · all Q&A threads

Unified home for biology, economics, statistics/methodology, engineering, and welfare discussion. Organized by domain.

Currently seeking bio / engineering expert input

#12 Hydrolysates: how confident are we they’ll replace amino acids in basal media? — 🧑 human-drafted
#17 Is cell density correlated with the cost/L of basal media? — 🤝 human-drafted, verifying a Claude take

See all via the bio_engineering_expert label →

Seed topics (reply below or start a new thread)

Domain	Thread	Scope
Media, amino acids & nutrients	#9 Pharma-grade media at $0.50–2.50/L?	Media cost range; CM_14 / CM_15 / CM_17
Growth factors & biotech	#13 Growth factors & hydrolysates to 2036	CM_12 / CM_13 / CM_18 / CM_19
Bioreactors, cell density & scale-up	#14 Bioreactors, cell density & scale-up	CM_16 / CM_17 / CM_20; CAPEX
Statistics & methodology	#10 Maturity-factor correlation	Latent factor; WACC / reactor / tech coupling
Welfare & impact	#15 Welfare comparison & counterfactuals	CM_02 / CM_10 / CM_11 (substance)

Start a new substantive thread →

Provenance tags: 🧑 human-drafted · 🤖 AI-generated · 🤝 human-refined from AI / verifying an AI take.

Process / Meta (split by activity)

Three separate hubs for three distinct coordination tasks. Substantive content does not live here — it lives in the Substantive hub above.

Workshop logistics

Hub: #2 Workshop logistics & process hub · category: General · all General threads

Session prep, scheduling, agenda, format, follow-ups for the May 2026 workshop.

Seed topics: (None yet.)

Start a new workshop-logistics thread →

PQ framing & operationalization

Hub: #4 PQ framing hub · category: Ideas · all Ideas threads

How we frame the Pivotal Questions — resolution criteria, jurisdiction forks, retiring/splitting PQs, operationalization of sub-questions CM_12–CM_20.

PQ	Framing seed	Metaculus
CM_01 — Focal cost	#5	link
CM_03 — Predict-experts (cost)	#6	link
CM_10 — Predict-experts (welfare)	#7	link
CM_11 — Direct welfare	#8	link

Substantive discussion of these PQs (actual estimates, counterfactual reasoning) lives in the Substantive hub (#3), not in the per-PQ framing seeds.

Start a new PQ framing thread →

Platform, UX & commenting process

Hub: #16 Platform, UX, page formatting & commenting · category: Ideas

Dashboard UX, visualization design, page organization, documentation clarity, commenting tools (Hypothesis vs Discussions vs giscus), and the structure of this discussion space itself.

Start a new platform / UX / process thread →

External resources

This map is maintained by hand. If a thread is missing or the map feels stale, ping us via any of the channels above and we’ll update it.

--- title: "Discussion Map" subtitle: "Where to ask, debate, and contribute — substantive discussion is unified; process is split by activity" format: html: include-in-header: text: | <script src="https://hypothes.is/embed.js" async></script> --- **Quick links:** [All GitHub Discussions](https://github.com/unjournal/cm_pq_modeling/discussions) · [Substantive hub (#3)](https://github.com/unjournal/cm_pq_modeling/discussions/3) · [PQ framing hub (#4)](https://github.com/unjournal/cm_pq_modeling/discussions/4) · [Workshop hub (#2)](https://github.com/unjournal/cm_pq_modeling/discussions/2) · [Platform & UX hub (#16)](https://github.com/unjournal/cm_pq_modeling/discussions/16) --- ## The structure **Substantive discussion is unified.** Biology, economics, statistics, engineering, and welfare debates happen in one place — the [Substantive discussion hub](https://github.com/unjournal/cm_pq_modeling/discussions/3) — rather than fragmenting across Workshop / Model / PQ silos. **Process discussion is split by activity** — three separate hubs for three distinct coordination tasks: workshop logistics, PQ framing, and platform/UX. GitHub Discussions is a flat stack of threads per category; the structure below is maintained by hand. ## Quick decision tree | I want to... | Use... | |---|---| | Comment on a specific line, paragraph, parameter, or equation | [**Hypothesis**](https://hypothes.is/) — click the `<` tab on the right edge of any dashboard page (a free Hypothesis account is required, signup takes ~30 seconds) | | Debate actual cost values, biology, engineering, welfare, or methodology | [**Substantive hub (#3)**](https://github.com/unjournal/cm_pq_modeling/discussions/3) | | Discuss how to *frame* a Pivotal Question (resolution, jurisdiction fork, retiring/splitting) | [**PQ framing hub (#4)**](https://github.com/unjournal/cm_pq_modeling/discussions/4) | | Discuss workshop logistics, scheduling, session format | [**Workshop hub (#2)**](https://github.com/unjournal/cm_pq_modeling/discussions/2) | | Suggest UX, visual, page-layout, or commenting-tool improvements | [**Platform & UX hub (#16)**](https://github.com/unjournal/cm_pq_modeling/discussions/16) | | Report a code bug | [**GitHub Issues**](https://github.com/unjournal/cm_pq_modeling/issues) | Reading GitHub Discussions is open to everyone; posting requires a free GitHub account. --- # Substantive discussion (unified) **Hub:** [#3 Substantive discussion hub](https://github.com/unjournal/cm_pq_modeling/discussions/3) · category: **Q&A** · [all Q&A threads](https://github.com/unjournal/cm_pq_modeling/discussions/categories/q-a) Unified home for biology, economics, statistics/methodology, engineering, and welfare discussion. Organized by domain. ### Currently seeking bio / engineering expert input - [**#12** Hydrolysates: how confident are we they'll replace amino acids in basal media?](https://github.com/unjournal/cm_pq_modeling/discussions/12) — 🧑 *human-drafted* - [**#17** Is cell density correlated with the cost/L of basal media?](https://github.com/unjournal/cm_pq_modeling/discussions/17) — 🤝 *human-drafted, verifying a Claude take* [See all via the `bio_engineering_expert` label →](https://github.com/unjournal/cm_pq_modeling/discussions?discussions_q=is%3Aopen+label%3Abio_engineering_expert) ### Seed topics (reply below or start a new thread) | Domain | Thread | Scope | |---|---|---| | Media, amino acids & nutrients | [**#9** Pharma-grade media at $0.50–2.50/L?](https://github.com/unjournal/cm_pq_modeling/discussions/9) | Media cost range; CM_14 / CM_15 / CM_17 | | Growth factors & biotech | [**#13** Growth factors & hydrolysates to 2036](https://github.com/unjournal/cm_pq_modeling/discussions/13) | CM_12 / CM_13 / CM_18 / CM_19 | | Bioreactors, cell density & scale-up | [**#14** Bioreactors, cell density & scale-up](https://github.com/unjournal/cm_pq_modeling/discussions/14) | CM_16 / CM_17 / CM_20; CAPEX | | Statistics & methodology | [**#10** Maturity-factor correlation](https://github.com/unjournal/cm_pq_modeling/discussions/10) | Latent factor; WACC / reactor / tech coupling | | Welfare & impact | [**#15** Welfare comparison & counterfactuals](https://github.com/unjournal/cm_pq_modeling/discussions/15) | CM_02 / CM_10 / CM_11 (substance) | **[Start a new substantive thread →](https://github.com/unjournal/cm_pq_modeling/discussions/new?category=q-a)** *Provenance tags: 🧑 human-drafted · 🤖 AI-generated · 🤝 human-refined from AI / verifying an AI take.* --- # Process / Meta (split by activity) Three separate hubs for three distinct coordination tasks. Substantive content does **not** live here — it lives in the Substantive hub above. ## Workshop logistics {#workshop} **Hub:** [#2 Workshop logistics & process hub](https://github.com/unjournal/cm_pq_modeling/discussions/2) · category: **General** · [all General threads](https://github.com/unjournal/cm_pq_modeling/discussions/categories/general) Session prep, scheduling, agenda, format, follow-ups for the [May 2026 workshop](https://uj-cm-workshop.netlify.app/). **Seed topics:** *(None yet.)* **[Start a new workshop-logistics thread →](https://github.com/unjournal/cm_pq_modeling/discussions/new?category=general)** ## PQ framing & operationalization {#pq-framing} **Hub:** [#4 PQ framing hub](https://github.com/unjournal/cm_pq_modeling/discussions/4) · category: **Ideas** · [all Ideas threads](https://github.com/unjournal/cm_pq_modeling/discussions/categories/ideas) *How* we frame the Pivotal Questions — resolution criteria, jurisdiction forks, retiring/splitting PQs, operationalization of sub-questions CM_12–CM_20. | PQ | Framing seed | Metaculus | |---|---|---| | **CM_01** — Focal cost | [#5](https://github.com/unjournal/cm_pq_modeling/discussions/5) | [link](https://www.metaculus.com/c/unjournal/38815/) | | **CM_03** — Predict-experts (cost) | [#6](https://github.com/unjournal/cm_pq_modeling/discussions/6) | [link](https://www.metaculus.com/c/unjournal/39317/) | | **CM_10** — Predict-experts (welfare) | [#7](https://github.com/unjournal/cm_pq_modeling/discussions/7) | [link](https://www.metaculus.com/c/unjournal/40617/) | | **CM_11** — Direct welfare | [#8](https://github.com/unjournal/cm_pq_modeling/discussions/8) | [link](https://www.metaculus.com/c/unjournal/40925/) | **Substantive** discussion of these PQs (actual estimates, counterfactual reasoning) lives in the [Substantive hub (#3)](https://github.com/unjournal/cm_pq_modeling/discussions/3), not in the per-PQ framing seeds. **[Start a new PQ framing thread →](https://github.com/unjournal/cm_pq_modeling/discussions/new?category=ideas)** ## Platform, UX & commenting process {#platform} **Hub:** [#16 Platform, UX, page formatting & commenting](https://github.com/unjournal/cm_pq_modeling/discussions/16) · category: **Ideas** Dashboard UX, visualization design, page organization, documentation clarity, commenting tools (Hypothesis vs Discussions vs giscus), and the structure of this discussion space itself. **[Start a new platform / UX / process thread →](https://github.com/unjournal/cm_pq_modeling/discussions/new?category=ideas)** --- ## External resources - 📊 [Interactive model dashboard](https://unjournal.github.io/cm_pq_modeling/) - 📖 [Technical docs](https://unjournal.github.io/cm_pq_modeling/docs.html) - 🔬 [Learn: how cultured chicken is made](https://unjournal.github.io/cm_pq_modeling/learn.html) - 🆚 [TEA comparison](https://unjournal.github.io/cm_pq_modeling/compare.html) - 🧑‍🏫 [Workshop site](https://uj-cm-workshop.netlify.app) - 🎯 [Pivotal Questions landing](https://info.unjournal.org/pivotal-questions.html) - 📘 [PQ background (GitBook)](https://globalimpact.gitbook.io/the-unjournal-project-and-communication-space/pivotal-questions) - 💻 [GitHub repo](https://github.com/unjournal/cm_pq_modeling) --- *This map is maintained by hand. If a thread is missing or the map feels stale, ping us via any of the channels above and we'll update it.*